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Commit 4a5d3ab3 authored by Arnaud Duvermy's avatar Arnaud Duvermy
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Update README.md

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% Counts simulations & DESEQ2 investigations
#Counts simulations & DESEQ2 investigations
Purpose:
1) Understand how DESEQ2 works
......@@ -6,7 +6,7 @@ Purpose:
2) Refined biological protocol (seqeuncing effort, ...)
# About DESEQ2
## About DESEQ2
The differential expression analysis uses a generalized linear model of the form:
Kij ∼ NB(µij , α i )
......@@ -24,11 +24,11 @@ Experiments without replicates do not allow for estimation of the dispersion of
expected value for each group, which is critical for differential expression analysis. Analysis with-out replicates is no longer supported since v1.22.
# Investigation of µ effect
## Investigation of µ effect
<img src="./img/fig_mu_effect.svg">
# Investigation of µ effect
## Investigation of alpha effect
<img src="./img/fig_size_effect.svg">
......
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