The simulation process in HTRfit has been optimized to generate RNAseq counts for 30,000 genes and 4,000 experimental conditions, each replicated 4 times, resulting in a total of 16,000 samples, in less than 5 minutes. However, the object generated by the framework under these conditions can consume a significant amount of RAM, approximately 50 GB. For an equivalent simulation with 6,000 genes, less than a minute and 10 GB of RAM are required.
The simulation process in HTRfit has been optimized to generate RNAseq counts for 30,000 genes and 4,000 experimental conditions (2000 levels in varA, 2 levels in varB), each replicated 4 times, resulting in a total of 16,000 samples, in less than 5 minutes. However, the object generated by the framework under these conditions can consume a significant amount of RAM, approximately 50 GB. For an equivalent simulation with 6,000 genes, less than a minute and 10 GB of RAM are required.
