The iterative alignment gives more reads in general but less around the diagonal, in opposite with cutsite and parasplit which give more contacts, especially around the diagonal.
The iterative alignment gives more reads in general but less around the diagonal, in opposite with cutsite and parasplit which give more contacts, especially around the diagonal.
Parasplit vs cutsite | Chr3 | Chr3 not normalized
#### Parasplit vs cutsite
All chromosomes (4kb, norm to 1) | Chromosome 3 (1kb, norm to 1) | Chromosome 3 (1kb, not normalized)
@@ -63,7 +68,8 @@ No filter vs filter | No filter vs filter pcr | No filter vs bot
...
@@ -63,7 +68,8 @@ No filter vs filter | No filter vs filter pcr | No filter vs bot
We can see a red line around the diagonal for the filtering, and some random adding and losing of contacts for the duplicate filtering. For the combination it doesn't seem different at first look.
We can see a red line around the diagonal for the filtering, and some random adding and losing of contacts for the duplicate filtering. For the combination it doesn't seem different at first look.
If we look at these matrices without normalization:
If we look at these matrices without normalization:
No filter vs filter not normalized | No filter vs filter pcr not normalized | No filter vs both not normalized
#### Chromosome 3 (1kb, **not** normalized)
No filter vs filter | No filter vs filter pcr | No filter vs both