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TreeFrog scRNASeq
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eeae83e8
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eeae83e8
authored
Jul 08, 2022
by
Laurent Modolo
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update dea
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@@ -21,26 +21,12 @@ classoption: aspectratio=169
## Program
1. Single-cell RNASeq data from 10X Sequencing (Friday 3 June 2022 - 14:00)
2. Normalization and spurious effects (Wednesday 8 June 2022 - 14:00)
3. Dimension reduction and data visualization (Monday 13 June 2022 - 15:00)
4. Clustering and annotation (Thursday 30 June 2022 2022 - 14:00)
5. Pseudo-time and velocity inference (Friday 8 July 2022 - 14:00)
6. Differential expression analysis (Monday 11 July 2022 - 15:30)
## Program
1. Single-cell RNASeq data from 10X Sequencing (Friday 3 June 2022 - 14:00)
2. Normalization and spurious effects (Wednesday 8 June 2022 - 14:00)
3. Dimension reduction and data visualization (Monday 13 June 2022 - 15:00)
4. Clustering and annotation (Thursday 30 June 2022 2022 - 14:00)
5. Pseudo-time and velocity inference (Friday 8 July 2022 - 14:00)
- Parametric versus non-parametric testing
- Differential expression analysis between groups
- Regression analysis
- Multiple testing
- Multivariate Differential expression analysis
6. Differential expression analysis (Monday 11 July 2022 - 15:30)
# Hypothesis testing
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@@ -58,8 +44,9 @@ classoption: aspectratio=169
\item $H_1$: the gene pression is not the same between the $2$ groups
\end{itemize}
\begin{center}
\bf We reject $H_0$ with a given risk $\alpha$ and a power $\beta$
{
\bf We reject $H_0$ with a given risk $\alpha$ and a power $\beta$
}
\end{center}
## Hypothesis testing
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@@ -74,11 +61,10 @@ classoption: aspectratio=169
## Hypothesis testing
\begin{center}
\href{https://en.wikipedia.org/
wiki/Power_of_a_test#/media/File:Statistical_test,_significance_level,_power.png
}{
\href{https://en.wikipedia.org/}{
\includegraphics[width=0.6\textwidth]{img/alpha_beta.png}
}
\end{center}
# Parametric versus non-parametric testing
# Differential expression analysis between groups
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