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Commit 307c1252 authored by fduveau's avatar fduveau
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Update 01-theoryBehindHtrfit.Rmd

Correction RNAseq -> RNA-seq
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...@@ -17,8 +17,8 @@ knitr::opts_chunk$set( ...@@ -17,8 +17,8 @@ knitr::opts_chunk$set(
``` ```
In the realm of RNAseq analysis, various key experimental parameters play a crucial role in influencing the statistical power to detect expression changes. Parameters such as sequencing depth, the number of replicates, and others are expected to impact statistical power. In the realm of RNA-seq analysis, various key experimental parameters play a crucial role in influencing the statistical power to detect expression changes. Parameters such as sequencing depth, the number of replicates, and others are expected to impact statistical power.
To navigate the selection of optimal values for these experimental parameters, we introduce a comprehensive statistical framework known as HTRfit, underpinned by computational simulation. Moreover, HTRfit offers seamless compatibility with DESeq2 outputs, facilitating a comprehensive evaluation of RNAseq analysis. To navigate the selection of optimal values for these experimental parameters, we introduce a comprehensive statistical framework known as HTRfit, underpinned by computational simulation. Moreover, HTRfit offers seamless compatibility with DESeq2 outputs, facilitating a comprehensive evaluation of RNA-seq analysis.
# HTRfit simulation workflow # HTRfit simulation workflow
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