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nf-core/hic: Changelog

The format is based on Keep a Changelog and this project adheres to Semantic Versioning.

v1.2.0dev

Added

  • Bump v1.2.0dev
  • Merge template nf-core 1.9
  • Move some options to camel_case
  • Update conda environment file
  • Update python scripts for python3

Deprecated

  • --skipMaps, --skipIce, --skipCool, --skipMultiQC are deprecated and replaced by --skip_maps, --skip_ice, --skip_cool, --skip_multiqc
  • --saveReference, --saveAlignedIntermediates, --saveInteractionBAM are replaced by --save_reference, --save_aligned_intermediates, --save_interaction_bam

v1.1.1

Fixed

  • Fix bug in tag. Remove '['

v1.1.0 - 2019-10-15

Added

  • Update hicpro2higlass with -p parameter
  • Support 'N' base motif in restriction/ligation sites
  • Support multiple restriction enzymes/ligattion sites (comma separated) (#31)
  • Add --saveInteractionBAM option
  • Add DOI (#29)
  • Update manual (#28)

Fixed

  • Fix bug for reads extension _1/_2 (#30)

v1.0 - [2019-05-06]

Initial release of nf-core/hic, created with the nf-core template.

Added

First version of nf-core Hi-C pipeline which is a Nextflow implementation of the HiC-Pro pipeline. Note that all HiC-Pro functionalities are not yet all implemented. The current version supports most protocols including Hi-C, in situ Hi-C, DNase Hi-C, Micro-C, capture-C or HiChip data.

In summary, this version allows :

  • Automatic detection and generation of annotation files based on igenomes if not provided.
  • Two-steps alignment of raw sequencing reads
  • Reads filtering and detection of valid interaction products
  • Generation of raw contact matrices for a set of resolutions
  • Normalization of the contact maps using the ICE algorithm
  • Generation of cooler file for visualization on higlass
  • Quality report based on HiC-Pro MultiQC module