diff --git a/src/RNA_Seq.nf b/src/RNA_Seq.nf index 0a1baf5bb94cd8cfe38ec079dc53d793582087ad..cdfcaa6b07971207261c8c107f5b01cabb0bf0b9 100644 --- a/src/RNA_Seq.nf +++ b/src/RNA_Seq.nf @@ -109,5 +109,60 @@ bedtools getfasta -name \ """ } +/* +* Kallisto : +* Imputs : fastq files +* Imputs : fasta files +* Output : bam files +*/ + +/* fasta indexing */ + + +process index_fasta { + tag "$fasta.baseName" + publishDir "results/mapping/index/", mode: 'copy' + + input: + file fasta from fasta_file + + output: + file "*.index*" into index_files + + script: +""" +kallisto index -k 31 --make-unique -i ${fasta.baseName}.index ${fasta} \ +> ${fasta.baseName}_kallisto_report.txt +""" +} + + +/* +* for paired-end data +*/ + +process mapping_fastq { + tag "$reads" + cpus 4 + publishDir "results/mapping/quantification/", mode: 'copy' + + input: + file reads from fastq_files_trim + file index from index_files.toList() + + output: + file "*" into counts_files + + script: +""" +mkdir ${reads[0].baseName} +kallisto quant -i ${index} -t ${task.cpus} \ +--bias --bootstrap-samples 100 -o ${reads[0].baseName} \ +${reads[0]} ${reads[1]} &> ${reads[0].baseName}_kallisto_report.txt +""" +} + + +