diff --git a/vignettes/htrfit.Rmd b/vignettes/htrfit.Rmd index 38619891eaecd9b971fc664e0b7ab094db9d12f4..56f5478f12a7c8efb5ee54ca613fd9e990dfcec4 100644 --- a/vignettes/htrfit.Rmd +++ b/vignettes/htrfit.Rmd @@ -503,6 +503,8 @@ l_tmb <- fitModelParallel(formula = kij ~ varB + (varB | varA), family = glmmTMB::nbinom2(link = "log"), log_file = "log.txt", n.cores = 1) +## -- output +l_tmb$gene1 ## -- evaluation resSimu <- simulationReport(mock_data, list_tmb = l_tmb, @@ -519,3 +521,9 @@ resSimu$dispersionEvaluation$disp_plot resSimu$roc_plot ``` +# About mixed model evaluation + +**HTRfit** offers a versatile simulation framework capable of fitting various types of models involving mixed effects, thanks to its implementation of **glmmTMB**. By combining the functionalities of `init_variable()` and `add_interaction()`, **HTRfit** enables the simulation of even the most complex experimental designs. However, it's important to note that as of now, HTRfit supports the evaluation of only *Type I* mixed models. In this context, *Type I* models are defined as those that follow the structure: `~ varA + (1 | varB)` or `~ varA + (varA | varB)`. Models not conforming to this specific form cannot be evaluated using **HTRfit's** current implementation. Nonetheless, you are welcome to extend its capabilities by implementing support for additional model types. + + +