From 30fd4df7f6b5f0b8a76dd4c511090965c5715204 Mon Sep 17 00:00:00 2001
From: cfournea <camille.fourneaux@ens-lyon.fr>
Date: Wed, 8 Feb 2023 15:29:53 +0100
Subject: [PATCH] Update README.md

---
 README.md | 22 +++++++++++++++++++++-
 1 file changed, 21 insertions(+), 1 deletion(-)

diff --git a/README.md b/README.md
index 660b527..d98e8e5 100644
--- a/README.md
+++ b/README.md
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-# Sister cells
+# Sister and cousin-cells data analysis
 
+## CD34+ dataset
+
+## T2EC sister-cells dataset
+
+- T2EC_sister_cells_1_filtering_normalization.R
+This script allows for data filtering and normalization, output a normalized matrix.
+
+- T2EC_sister_cells_2_distances_analysis.R
+This script allows to calculate Manhattan distances between pairs of cells, compares the mean Manhattan distance between sister-cells and randomly paired cells and plot the results (figure 4 B, D, E).
+
+- T2EC_sister_cells_3_MEM_analysis.R
+This script applies a mixed effect model on the dataset to identify genes for which there exist a stastical correlation of expression between sister-cells and plot the results (figure 6).
+
+## T2EC cousin-cells dataset
+
+- T2EC_cousins_cells_1_filtering_normalization.Rmd
+This script allows for data filtering and normalization, output a normalized matrix.
+
+- T2EC_cousins_cells_2_distances_analysis.Rmd
+This script allows to calculate Manhattan distances between pairs of cells, compares the mean Manhattan distance between sister-cells and randomly paired cells, cousin-cells and randomly paired cells and plot the results (figure 5).
-- 
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