diff --git a/Readme.md b/Readme.md
index 0581f966395580e58bf6e47be22423f0db621827..ee8f4e59832e1865989dd4d4e415167c07295453 100644
--- a/Readme.md
+++ b/Readme.md
@@ -118,7 +118,7 @@ The design parameter must have the following structure:
 
 1. The `count_files`columns must contain the name of the file **without its path** (as it is given with the --path argument).
 2. The `sample` column  must contain the name of the sample
-3. The `condition` column, the name of the condition
+3. The `condition` column, the name of the condition. Note that unlike the two previous columns, **this column can be renamed** (e.g condition can be rename to treatment)
 
 The columns must be `tab-separated`.