diff --git a/README.md b/README.md
index 365d32607f83e1cb47dd378f2cebf56a2d52e737..5d4bbf4abc52556ca9b14a19dbab359c54235527 100644
--- a/README.md
+++ b/README.md
@@ -19,6 +19,16 @@ This project requires `python>=3.8` to work correctly and the following modules
 * seaborn>=0.10.1
 * matplotlib>=3.1.2
 
+## Build the Sphinx documentation
+
+The documentation was build using `Sphinx`.
+
+To build the documentation (which contains this document and the Api of the program), go in the doc folder and enter: 
+
+```console
+$ make html
+```
+
 ## Usage
 
 ### `gc_content` module
@@ -105,4 +115,4 @@ The figure to give to the `--norm` parameter must be defined like this:
 
 * The column condition must contain the same conditions defined in the `condition` column of the design file. 
 * The column replicate must contain the same replicates names in the `replicate` column of the design file.
-* The column coef contain a value used to normalise the coverage
\ No newline at end of file
+* The column coef contain a value used to normalise the coverage