diff --git a/src/nextflow.config b/src/nextflow.config
index dfebf4d31a76c838e52220135f1a430972d1d698..df01d720d2cf26b934e32739a9cced9e7b3d209b 100644
--- a/src/nextflow.config
+++ b/src/nextflow.config
@@ -17,6 +17,7 @@ profiles {
     docker.temp = "auto"
     docker.enabled = true
     process {
+      memory = '16 GB'
       withLabel: big_mem_mono_cpus {
         cpus = 1
       }
@@ -29,6 +30,7 @@ profiles {
     singularity.enabled = true
     singularity.cacheDir = "./bin/"
     process {
+      memory = '16 GB'
       withLabel: big_mem_mono_cpus {
         cpus = 1
       }
@@ -46,7 +48,7 @@ profiles {
         executor = "sge"
         clusterOptions = "-cwd -V"
         cpus = 1
-        memory = "20GB"
+        memory = "128GB"
         time = "12h"
         queue = "monointeldeb128"
       }
@@ -55,7 +57,7 @@ profiles {
         executor = "sge"
         clusterOptions = "-cwd -V"
         cpus = 32
-        memory = "30GB"
+        memory = "192GB"
         time = "24h"
         queue = "CLG6242deb384A,CLG6242deb384C,CLG5218deb192A,CLG5218deb192B,CLG5218deb192C,CLG5218deb192D"
         penv = "openmp32"
@@ -75,6 +77,7 @@ profiles {
         executor = "sge"
         clusterOptions = "-P P_lbmc -l os=cl7 -l sps=1 -r n"
         cpus = 1
+        memory = "8GB"
         queue = "huge"
       }
       withLabel: big_mem_multi_cpus {
@@ -83,9 +86,9 @@ profiles {
         stageInMode = "copy"
         stageOutMode = "rsync"
         executor = "sge"
-        clusterOptions = "-P P_lbmc -l os=cl7 -l sps=1 -r n\
-        "
+        clusterOptions = "-P P_lbmc -l os=cl7 -l sps=1 -r n"
         cpus = 1
+        memory = "8GB"
         queue = "huge"
       }
     }
diff --git a/src/nf_modules/picard/main.nf b/src/nf_modules/picard/main.nf
index 9a6b702fa48cfbbb0d2d95ac8a0f8ae9f5e22e76..0faec2e001ce79e92c6377abfc07e2a7b6138b22 100644
--- a/src/nf_modules/picard/main.nf
+++ b/src/nf_modules/picard/main.nf
@@ -6,7 +6,6 @@ process mark_duplicate {
   label "big_mem_mono_cpus"
   tag "$file_id"
   publishDir "results/mapping/ddup/", mode: 'copy'
-  memory '30 GB'
 
   input:
     tuple val(file_id), path(bam)