diff --git a/nextflow.config b/nextflow.config
index eebf7416dd0e9adfc3de34a82936edcf98c88b9c..f4f222fab0b5b80e3e5d3ea713107d6046ce19fc 100644
--- a/nextflow.config
+++ b/nextflow.config
@@ -133,7 +133,7 @@ params {
 
     // Max resource options
     // Defaults only, expecting to be overwritten
-    max_memory                 = '128.GB'
+    max_memory                 = '64.GB'
     max_cpus                   = 16
     max_time                   = '240.h'
 
diff --git a/nextflow_schema.json b/nextflow_schema.json
index bcc53ce10d3bc56d29b9d91bbc164b365fda1b82..0547eed6628e7b9c3395f4b92779e7b62f3847d8 100644
--- a/nextflow_schema.json
+++ b/nextflow_schema.json
@@ -423,7 +423,7 @@
                 "max_memory": {
                     "type": "string",
                     "description": "Maximum amount of memory that can be requested for any single job.",
-                    "default": "128.GB",
+                    "default": "64.GB",
                     "fa_icon": "fas fa-memory",
                     "pattern": "^\\d+(\\.\\d+)?\\.?\\s*(K|M|G|T)?B$",
                     "hidden": true,